CAS 35619-65-9|Tritiozine

Introduction：Basic information about CAS 35619-65-9|Tritiozine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Tritiozine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Tritiozine
CAS Number	35619-65-9	Molecular Weight	297.37000
Density	1.211g/cm3	Boiling Point	420.8ºC at 760mmHg
Molecular Formula	C₁₄H₁₉NO₄S	Melting Point	141-143°
MSDS	/	Flash Point	208.3ºC

Names

Name	morpholin-4-yl-(3,4,5-trimethoxyphenyl)methanethione
Synonym	More Synonyms

Tritiozine BiologicalActivity

Description	Trithiozine is an orally active antisecretory and antiulcer agent. Trithiozine can be used for the research of peptic ulcer disease and hypersecretory disorders[1].
Related Catalog	Research Areas >>EndocrinologySignaling Pathways >>Others >>Others
In Vivo	Trithiozine (T) (i. p., oral, i. v.; 50 mg/kg, 200 mg/kg) shows a considerable antisecretory and antiulcer activity on different experimental models in the rats and dogs[1]. Animal Model: female Sprague-Dawley rats and male beagle dogs[1] Dosage: 50 mg/kg (rats); 200 mg/kg or 50 mg/kg (dogs) Administration: i. p., single (rats); oral, single or i. v. (dogs) Result: Showed an apparent plasma half-life of about 2.5 h in rats and 1 h in dogs and rapidly metabolized yielding two metabolites and two conjugates.
References	[1]. G. M. Pacifici, et al. Pharmacokinetics and biotransformation, in rats and dogs, of trithiozine, a new antisecretory drug. , 1(3), 141–147. doi:10.1007/bf03189268.

Chemical & Physical Properties

Density	1.211g/cm3
Boiling Point	420.8ºC at 760mmHg
Melting Point	141-143°
Molecular Formula	C₁₄H₁₉NO₄S
Molecular Weight	297.37000
Flash Point	208.3ºC
Exact Mass	297.10300
PSA	72.25000
LogP	1.65800
Index of Refraction	1.57
InChIKey	MVOUIYUWRXPNKD-UHFFFAOYSA-N
SMILES	COc1cc(C(=S)N2CCOCC2)cc(OC)c1OC

Synonyms

EINECS 252-645-4

Tritiozine

Tresanil

Tritiozina [INN-Spanish]

Tritiozina [Italian]

ISF 2001

4-(3',4',5'-trimethoxyphenyl)-thioxomethylmorpholine

Trithiozine

4-(3,4,5-Trimethoxythiobenzoyl)morpholine

Tritiozinum [INN-Latin]

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