CAS 9001-03-0|Carbonic anhydrase

Introduction:Basic information about CAS 9001-03-0|Carbonic anhydrase, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCarbonic anhydrase
CAS Number9001-03-0Molecular Weight/
Density/Boiling Point/
Molecular Formula/Melting Point/
MSDSChineseUSAFlash Point/
Symbol
GHS07
Signal WordWarning

Names

NameDehydratase, Carbonate
SynonymMore Synonyms

Carbonic anhydrase BiologicalActivity

DescriptionCarbonic anhydrase is ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. Carbonic anhydrase can catalyze reversible conversion of carbon dioxide to bicarbonate and protons. Carbonic anhydrase can be used for the research of cancer, glaucoma, obesity and epilepsy[1][2].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>Carbonic AnhydraseResearch Areas >>Metabolic DiseaseResearch Areas >>Neurological Disease
References

[1]. Kanchan Aggarwal, et al. In Situ Photoregulation of Carbonic Anhydrase Activity Using Azobenzenesulfonamides. Biochemistry. 2019 Jan 8;58(1):48-53.  

[2]. Vladimir Amirkhanov, et al. Pharmacophores Modeling in Terms of Prediction of Theoretical Physicochemical Properties and Verification by EXPERIMENTAL correlations of Carbacylamidophosphates (CAPh) and Sulfanylamidophosphates (SAPh) Tested as New Carbonic Anhydrase Inhibitors. Mini Rev Med Chem. 2019;19(12):1015-1027.  

Chemical & Physical Properties

Storage condition2-8°C

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH319
Precautionary StatementsP305 + P351 + P338
Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesB,Xi,T
Risk Phrases36-41-40-37/38-24-20/22
RIDADRNONH for all modes of transport
WGK Germany3.0

Articles106

More Articles
Local pH domains regulate NHE3-mediated Na⁺ reabsorption in the renal proximal tubule.

Am. J. Physiol. Renal Physiol. 307(11) , F1249-62, (2014)

The proximal tubule Na(+)/H(+) exchanger 3 (NHE3), located in the apical dense microvilli (brush border), plays a major role in the reabsorption of NaCl and water in the renal proximal tubule. In resp...

Short peptides self-assemble to produce catalytic amyloids.

Nature Chemistry 6(4) , 303-9, (2014)

Enzymes fold into unique three-dimensional structures, which underlie their remarkable catalytic properties. The requirement to adopt a stable, folded conformation is likely to contribute to their rel...

Crystal structures of two tetrameric β-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora.

FEBS J. 281(7) , 1759-72, (2014)

Carbonic anhydrases (CAs) are metalloenzymes catalyzing the reversible hydration of carbon dioxide to bicarbonate (hydrogen carbonate) and protons. CAs have been identified in archaea, bacteria and eu...

Synonyms

MFCD00081467
ca1, bovine erythrocytes
ec 4.2.1.1
EINECS 232-576-6
ca, human liver
carbonic anhydrase
carbonate hydro-lyase
carbonate dehydratase
iub: 4.2.1.1
carbonic anhydrase bovine erythrocytes
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