CAS 9002-12-4|uricase
Introduction：Basic information about CAS 9002-12-4|uricase, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | uricase | ||
|---|---|---|---|
| CAS Number | 9002-12-4 | Molecular Weight | 567.398 |
| Density | / | Boiling Point | / |
| Molecular Formula | C18H26N5O14P | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS08 | Signal Word | Danger |
Names
| Name | Oxidase urate |
|---|---|
| Synonym | More Synonyms |
uricase BiologicalActivity
| Description | Urate oxidase (Uox), i.e., uricase, is often used in biochemical studies. Urate oxidase is a peroxisomal enzyme that catalyzes the oxidation of uric acid to allantoin in most mammals[1]. |
|---|---|
| Related Catalog | Research Areas >>Others |
| References | [1]. Wu XW, et al. Urate oxidase: primary structure and evolutionary implications. Proc Natl Acad Sci U S A. 1989 Dec;86(23):9412-6. |
Chemical & Physical Properties
| Molecular Formula | C18H26N5O14P |
|---|---|
| Molecular Weight | 567.398 |
| Exact Mass | 567.121399 |
| Appearance of Characters | lyophilized powder |
| InChIKey | VPXDHZMLJOJKOX-UHFFFAOYSA-N |
| SMILES | N.O=c1ccn(C2OC(COP(=O)(O)OC3C(CO)OC(n4ccc(=O)[nH]c4=O)C3O)C(O)C2O)c(=O)[nH]1 |
| Storage condition | −20°C |
| Water Solubility | Hardly soluble in water, slightly soluble in buffer alkaline solution. |
Safety Information
| Symbol | GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H334-H360FD |
| Precautionary Statements | P201-P261-P280-P284-P304 + P340-P308 + P313 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | YU7100000 |
Articles48
More Articles| Rasburicase in the prevention of laboratory/clinical tumour lysis syndrome in children with advanced mature B-NHL: a Children's Oncology Group Report. Br. J. Haematol. 163(3) , 365-72, (2013) Laboratory (LTLS) and clinical (CTLS) tumour lysis syndrome (TLS) are frequent complications in newly diagnosed children with advanced mature B cell non-Hodgkin lymphoma (B-NHL). Rasburicase, compared... | |
| Resolution of massive tophaceous gout with three urate-lowering drugs. Am. J. Med. 126(11) , e9-10, (2013) | |
| Reorganizing the protein space at the Universal Protein Resource (UniProt). Nucleic Acids Res. 40 , D71-D75, (2012) The mission of UniProt is to support biological research by providing a freely accessible, stable, comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with... |
Synonyms
| MFCD00082126 |
| Urate oxidase |
| Uric acid oxidase |
| Uratoxidase |
| Urate:O2-oxidoreductase |
| EINECS 232-655-5 |
| Uricase |
| Uricozyme |
