CAS 9025-13-2|Native Pseudomonas sp. Creatinine amidohydrolase

Introduction:Basic information about CAS 9025-13-2|Native Pseudomonas sp. Creatinine amidohydrolase, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameNative Pseudomonas sp. Creatinine amidohydrolase
CAS Number9025-13-2Molecular Weight188.146
Density1.2±0.1 g/cm3Boiling Point194.5±35.0 °C at 760 mmHg
Molecular FormulaC9H7F3OMelting Point/
MSDSChineseUSAFlash Point78.1±17.4 °C

Names

NameCreatininase
SynonymMore Synonyms

BiologicalActivity

DescriptionCreatininase (Creatinine amidohydrolase; CAH), namely creatinine amidohydrolase, from Pseudomonas putida, is a homohexameric enzyme commonly used in biochemical research. Creatininase acts on carbon-nitrogen bonds other than peptide bonds, and can catalyze the hydrolysis of creatinine to creatine, which can then be metabolized by creatinase to urea and sarcosine[1].
Related CatalogResearch Areas >>Metabolic Disease
References

[1]. Barbara Beuth, et al. Crystal structure of creatininase from Pseudomonas putida: a novel fold and a case of convergent evolution. J Mol Biol. 2003 Sep 5;332(1):287-301.  

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point194.5±35.0 °C at 760 mmHg
Molecular FormulaC9H7F3O
Molecular Weight188.146
Flash Point78.1±17.4 °C
Exact Mass188.044907
LogP2.61
Appearance of Characterslyophilized powder
Vapour Pressure0.4±0.4 mmHg at 25°C
Index of Refraction1.453
InChIKeyJVVMUHJDTNMVHZ-UHFFFAOYSA-N
SMILESC#CC(O)C=CCCCCCCCCCCC=CC(O)C#C
Storage condition2-8°C

Safety Information

Personal Protective EquipmentEyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Safety Phrases22-24/25
RIDADRNONH for all modes of transport
WGK Germany3

Articles31

More Articles
Analytical expression of non-steady-state concentrations and current pertaining to compounds present in the enzyme membrane of biosensor.

J. Phys. Chem. A 115(17) , 4299-306, (2011)

A mathematical model of trienzyme biosensor at an internal diffusion limitation for a non-steady-state condition has been developed. The model is based on diffusion equations containing a linear term ...

Immobilization of creatininase, creatinase and sarcosine oxidase on iron oxide nanoparticles/chitosan-g-polyaniline modified Pt electrode for detection of creatinine.

Enzyme Microb. Technol. 50(4-5) , 247-54, (2012)

Commercial enzymes, creatininase (CA) from Pseudomonas sp, creatinase (CI) from Pseudomonas sp, sarcosine oxidase (SO) from Bacillus sp were co-immobilized onto iron oxide nanoparticles/chitosan-graft...

Amperometric creatinine biosensor based on covalently coimmobilized enzymes onto carboxylated multiwalled carbon nanotubes/polyaniline composite film.

Anal. Biochem. 419(2) , 277-83, (2011)

A mixture of commercial creatinine amidohydrolase (CA), creatine amidinohydrolase (CI), and sarcosine oxidase (SO) was coimmobilized covalently via N-ethyl-N'-(3-dimethylaminopropyl) carbodiimide (EDC...

Synonyms

Creatinine amidohydrolase
Ethanone, 2,2,2-trifluoro-1-(4-methylphenyl)-
2,2,2-Trifluoro-1-p-tolyl-ethanone
2,2,2-Trifluoro-1-(4-methylphenyl)ethanone
Creatinine amide hydrolase
Native Pseudomonas sp. Creatinine amidohydrolase
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