Introduction：Basic information about CAS 151126-32-8|Pramlintide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Pramlintide |
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| CAS Number | 151126-32-8 | Molecular Weight | 3949.43 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C171H269N51O53S2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Pramlintide |
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| Synonym | More Synonyms |
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Pramlintide BiologicalActivity
| Description | Pramlintide is a polypeptide analogue of human amylin. Pramlintide is an antidiabetic, is antineoplastic in colorectal cancer[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| In Vitro | Pramlintide inhibits the growth of HCT-116 and HT-29 in a dose-dependent manner, with higher efficacy against the latter (IC50s of 48.67 and 9.10 μg/mL, respectively)[1]. The addition of 5, 10, and 20 μg/mL of Pramlintide to HCT-116 and HT-29 with 5-fluorouracil, Oxaliplatin, or Irinotecan induces the antiproliferative effect synergistically[1]. |
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| References | [1]. Maha S Al-Keilani, et al. Pramlintide, an antidiabetic, is antineoplastic in colorectal cancer and synergizes with conventional chemotherapy. Clin Pharmacol. 2018 Mar 5;10:23-29. |
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Chemical & Physical Properties
| Molecular Formula | C171H269N51O53S2 |
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| Molecular Weight | 3949.43 |
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| Storage condition | -20℃ |
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Synonyms
