CAS 9028-48-2|Isocitrate dehydrogenase
| Common Name | Isocitrate dehydrogenase | ||
|---|---|---|---|
| CAS Number | 9028-48-2 | Molecular Weight | / |
| Density | / | Boiling Point | / |
| Molecular Formula | / | Melting Point | / |
| MSDS | USA | Flash Point | / |
Names
| Name | Isocitric dehydrogenase |
|---|---|
| Synonym | More Synonyms |
Isocitrate dehydrogenase BiologicalActivity
| Description | Isocitrate dehydrogenase (ICDH) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD(P)+ to NAD(P)H, it plays important roles in cellular metabolism[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Isocitrate Dehydrogenase (IDH)Research Areas >>Metabolic Disease |
| References | [1]. Reitman ZJ, Yan H. Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. J Natl Cancer Inst. 2010 Jul 7;102(13):932-41. |
Chemical & Physical Properties
| InChIKey | GQASXCYBZFOWQR-UHFFFAOYSA-N |
|---|---|
| SMILES | CC(=Cc1ccccc1)c1ccc2c(c1)C(C)(C)C(O)CC2(C)C.CC(=Cc1ccccc1)c1ccc2c(c1)C(C)(C)CC(O)C2(C)C |
| Storage condition | 2-8°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US) |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles94
More Articles| [Effect of glyphosate on the energy exchange in carp organs]. Ukr. Biokhim. Zh. 85(3) , 22-30, (2013) The use of glyphosate as a herbicide in agriculture can lead to the presence of its residues and metabolites (aminomethylphosphonic acid) in food for human consumption and pose a threat to health. The... | |
| Genetic features of oligodendrogliomas and presence of seizures. The relationship of seizures and genetics in LGOs. Clin. Neuropathol. 33(4) , 292-8, (2014) Low grade oligodendrogliomas (LGO) are diffusely infiltrating World Health Organization (WHO) grade II gliomas, 20 - 30% of which show contrast enhancement. Seizures are a common presenting feature. I... | |
| Controversies over the diagnosis of oligodendroglioma: a report from the satellite workshop at the 4th international symposium of brain tumor pathology, Nagoya Congress Center, May 23, 2012. Brain Tumor Pathol. 30(4) , 253-61, (2013) With the goal of discussing how the neuropathology community should resolve the controversy over the diagnosis of oligodendroglioma, this Satellite Workshop reflects the collaboration between two invi... |
Synonyms
| NADP-specific isocitric dehydyrogenase |
| NADPH-dependent isocitrate dehydrogenase |
| Oxalosuccinic decarboxylase |
| TPN-dependent isocitrate dehydrogenase |
| TPN-isocitrate dehydrogenase |
| TPN-linked isocitrate dehydrogenase |
| TPN-specific isocitrate dehydrogenase |
