Introduction：Basic information about CAS 1167421-25-1|UAA crosslinker 1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | UAA crosslinker 1 |
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| CAS Number | 1167421-25-1 | Molecular Weight | 259.26200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C9H17N5O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | N6-((2-azidoethoxy)carbonyl)-L-lysine |
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| Synonym | More Synonyms |
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UAA crosslinker 1 BiologicalActivity
| Description | UAA crosslinker 1 act as substrates for pylRS/tRNA pair that enable its incorporation into a target protein. |
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| Related Catalog | Signaling Pathways >>Antibody-drug Conjugate >>ADC LinkerResearch Areas >>Cancer |
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| References | [1]. VanBrunt MP, et al. Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody-Drug Conjugates Using Click Cycloaddition Chemistry. Bioconjug Chem. 2015 Nov 18;26(11):2249-60. |
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Chemical & Physical Properties
| Molecular Formula | C9H17N5O4 |
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| Molecular Weight | 259.26200 |
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| Exact Mass | 259.12800 |
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| PSA | 151.40000 |
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| LogP | 1.14906 |
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| InChIKey | RPLCQQYRZLXMKL-UHFFFAOYSA-N |
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| SMILES | [N-]=[N+]=NCCOC(=O)NCCCCC(N)C(=O)O |
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| Storage condition | -20C |
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Synonyms
| (S)-2-Amino-6-((2-azidoethoxy)carbonylamino)hexanoic acid |
| UAA crosslinker 1 |
