Introduction：Basic information about CAS 592542-61-5|(E)-Methyl 2-(2-Methoxy-5-((2′,4′,6′-triMethoxystyrylsulfonyl)Meth, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (E)-Methyl 2-(2-Methoxy-5-((2′,4′,6′-triMethoxystyrylsulfonyl)Methyl)phenylamino)acetate |
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| CAS Number | 592542-61-5 | Molecular Weight | 465.51700 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C22H27NO8S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (E)-methyl 2-(2-methoxy-5-((2',4',6'-trimethoxystyrylsulfonyl)methyl)phenylamino)acetate |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Anticancer agent 9, a glycine derivative, is an anticancer agent. Anticancer agent 9 can inhibit tumor cells viability of myelogenous leukemia and human prostate cancer[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| In Vitro | Anticancer agent 9 (compound 24) (96 h) inhibits the cell growth, with IC50s of 0.1 μM and 0.1 μM for K562 and DU145 cells, respectively[1]. |
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| References | [1]. Pallela VR, et, al. Hydrothiolation of benzyl mercaptan to arylacetylene: application to the synthesis of (E) and (Z)-isomers of ON 01910•Na (Rigosertib®), a phase III clinical stage anti-cancer agent. Org Biomol Chem. 2013 Mar 28;11(12):1964-77. |
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Chemical & Physical Properties
| Molecular Formula | C22H27NO8S |
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| Molecular Weight | 465.51700 |
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| Exact Mass | 465.14600 |
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| PSA | 117.77000 |
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| LogP | 4.04540 |
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| InChIKey | XQGFPRPZKFBYNA-CMDGGOBGSA-N |
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| SMILES | COC(=O)CNc1cc(CS(=O)(=O)C=Cc2c(OC)cc(OC)cc2OC)ccc1OC |
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Synonyms
| methyl-{N-[2-methoxy-5-methylene(2',4',6'-trimethoxystyrylsulfonyl)-phenyl]amino}acetate |
| methyl (E)-2-(5-((2,4,6-trimethoxystyrylsulfonyl)methyl)-2-methoxyphenylamino)acetate |
| methyl 2-(5-((2,4,6-trimethoxystyrylsulfonyl)methyl)-2-methoxyphenylamino)acetate |
| (E)-2,4,6-trimethoxystyryl-3-(carbomethoxymethylamino)-4-methoxybenzyl-sulfone |
| (E)-2,4,6-trimethoxystyryl 3-(carbomethoxymethylamno)-4-methoxybenzyl-sulfone |
