CAS 1276732-89-8|Carbidopa-d3

Introduction:Basic information about CAS 1276732-89-8|Carbidopa-d3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCarbidopa-d3
CAS Number1276732-89-8Molecular Weight229.25
Density1.4±0.1 g/cm3Boiling Point528.7±50.0 °C at 760 mmHg
Molecular FormulaC10H11D3N2O4Melting Point/
MSDS/Flash Point273.5±30.1 °C

Names

Name(s)-(-)-Carbidopa-d3
SynonymMore Synonyms

Carbidopa-d3 BiologicalActivity

DescriptionCarbidopa-d3 是 Carbidopa氘代物[1]。
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point528.7±50.0 °C at 760 mmHg
Molecular FormulaC10H11D3N2O4
Molecular Weight229.25
Flash Point273.5±30.1 °C
Exact Mass229.114182
LogP-0.19
Vapour Pressure0.0±1.5 mmHg at 25°C
Index of Refraction1.641

Synonyms

Benzene-2,3,6-d3-propanoic acid, α-hydrazinyl-4,5-dihydroxy-α-methyl-, (αS)-
(2S)-3-[3,4-Dihydroxy(2H3)phenyl]-2-hydrazino-2-methylpropanoic acid
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