CAS 75217-63-9|(Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt

Introduction:Basic information about CAS 75217-63-9|(Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt
CAS Number75217-63-9Molecular Weight3498.747
Density1.5±0.1 g/cm3Boiling Point/
Molecular FormulaC153H225N43O50SMelting Point/
MSDS/Flash Point/

Names

Name(Met(O)27)-Glucagon (1-29) (human, rat, porcine)
SynonymMore Synonyms

BiologicalActivity

Description(Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified glucagon. (Met(O)27)-Glucagon (1-29) (human, rat, porcine) has the same maximum glucose-synthesizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor[1].
Related CatalogResearch Areas >>Metabolic Disease
References

[1]. Nooijen WJ, et al. Immunogenicity and bioactivity of glucagon, modified at methionine-27. Horm Metab Res. 1979 Aug;11(8):459-63.  

Chemical & Physical Properties

Density1.5±0.1 g/cm3
Molecular FormulaC153H225N43O50S
Molecular Weight3498.747
Exact Mass3496.610596
LogP-7.58
Index of Refraction1.685
Storage condition-20°C

Synonyms

L-Leucinamide, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-L-seryl-L-arginyl-L-arg inyl-L-alanyl-L-glutaminyl-L-α-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-N-[(1S)-1-[[[(1S)-3-amino-1-[[[(1S,2R)-1-carboxy-2-hydroxypropyl]amino]carbonyl]-3-oxopropyl]amino]carbonyl
 ]-3-(methylsulfinyl)propyl]-
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