Introduction:Basic information about CAS 75217-63-9|(Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt |
|---|
| CAS Number | 75217-63-9 | Molecular Weight | 3498.747 |
|---|
| Density | 1.5±0.1 g/cm3 | Boiling Point | / |
|---|
| Molecular Formula | C153H225N43O50S | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | (Met(O)27)-Glucagon (1-29) (human, rat, porcine) |
|---|
| Synonym | More Synonyms |
|---|
BiologicalActivity
| Description | (Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified glucagon. (Met(O)27)-Glucagon (1-29) (human, rat, porcine) has the same maximum glucose-synthesizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor[1]. |
|---|
| Related Catalog | Research Areas >>Metabolic Disease |
|---|
| References | [1]. Nooijen WJ, et al. Immunogenicity and bioactivity of glucagon, modified at methionine-27. Horm Metab Res. 1979 Aug;11(8):459-63. |
|---|
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|
| Molecular Formula | C153H225N43O50S |
|---|
| Molecular Weight | 3498.747 |
|---|
| Exact Mass | 3496.610596 |
|---|
| LogP | -7.58 |
|---|
| Index of Refraction | 1.685 |
|---|
| Storage condition | -20°C |
|---|
Synonyms
| L-Leucinamide, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-L-seryl-L-arginyl-L-arg inyl-L-alanyl-L-glutaminyl-L-α-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-N-[(1S)-1-[[[(1S)-3-amino-1-[[[(1S,2R)-1-carboxy-2-hydroxypropyl]amino]carbonyl]-3-oxopropyl]amino]carbonyl
 ]-3-(methylsulfinyl)propyl]- |
| HSQGTFTSDYSKYLDSRRAQDFVQWLMNT |