Introduction：Basic information about CAS 144060-62-8|Febuxostat impurity 8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Febuxostat impurity 8 |
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| CAS Number | 144060-62-8 | Molecular Weight | 319.37500 |
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| Density | 1.268±0.06 g/cm3 | Boiling Point | / |
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| Molecular Formula | C16H17NO4S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-[3-formyl-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazole carboxylic acid |
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| Synonym | More Synonyms |
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Febuxostat impurity 8 BiologicalActivity
| Description | Febuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Manne Satyanarayana Reddy, et al. Process for preparation of 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylic acid and its pharmaceutically acceptable salts. WO2011141933A2. |
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Chemical & Physical Properties
| Density | 1.268±0.06 g/cm3 |
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| Molecular Formula | C16H17NO4S |
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| Molecular Weight | 319.37500 |
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| Exact Mass | 319.08800 |
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| PSA | 104.73000 |
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| LogP | 3.66400 |
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| InChIKey | OHIQHHXCAMMCPH-UHFFFAOYSA-N |
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| SMILES | Cc1nc(-c2ccc(OCC(C)C)c(C=O)c2)sc1C(=O)O |
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| Water Solubility | Practically insoluble (0.019 g/L) (25 ºC) |
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Synonyms
| 2-[3-formyl-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid |
| 2-[3-formyl-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylic acid |
| 2-(3-formyl-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid |
| 2-(3-formyl-4-isobutoxyphenyl)-4-methyl- 5-thiazolecarboxylic acid |
| 2-[3-formyl-4-(2-methylpropyloxy)phenyl]-4-methyl-5-thiazole formic acid |
| FBZC |
| Febuxostat Impurity 8 |
