CAS 1502655-48-2|Ledipasvir diacetone

Introduction：Basic information about CAS 1502655-48-2|Ledipasvir diacetone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Ledipasvir diacetone BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Ledipasvir diacetone
CAS Number	1502655-48-2	Molecular Weight	1005.16000
Density	/	Boiling Point	/
Molecular Formula	C₅₅H₆₆F₂N₈O₈	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	Ledipasvir diacetone
Synonym	More Synonyms

Ledipasvir diacetone BiologicalActivity

Description	Ledipasvir diacetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.
Related Catalog	Signaling Pathways >>Metabolic Enzyme/Protease >>HCV ProteaseSignaling Pathways >>Anti-infection >>HCVResearch Areas >>Infection
In Vitro	Ledipasvir diacetone is considered the active pharmaceutical ingredient, which is converted to Ledipasvir spray-dried dispersion, an amorphous free base.

Chemical & Physical Properties

Molecular Formula	C₅₅H₆₆F₂N₈O₈
Molecular Weight	1005.16000
Exact Mass	1004.50000
PSA	208.78000
LogP	10.45550
InChIKey	LXKDKHCANHWUPC-YGWQTYEPSA-N
SMILES	CC(C)=O.CC(C)=O.COC(=O)NC(C(=O)N1CC2(CC2)CC1c1ncc(-c2ccc3c(c2)C(F)(F)c2cc(-c4ccc5nc(C6C7CCC(C7)N6C(=O)C(NC(=O)OC)C(C)C)[nH]c5c4)ccc2-3)[nH]1)C(C)C
Storage condition	2-8℃

Synonyms

Methyl N-[(2S)-1-[(6S)-6-[5-[9,9-Difluoro-7-[2-[(1S,2S,4R)-3-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-3-azabicyclo[2.2.1]heptan-2-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate diacetone

GS-5885 diacetone

methyl ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate compound with propan-2-one (1:2)

Ledipasvir (diacetone)

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