Introduction：Basic information about CAS 208645-74-3|H-Gly-Gly-AMC hydrochloride salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | H-Gly-Gly-AMC hydrochloride salt |
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| CAS Number | 208645-74-3 | Molecular Weight | 289.28700 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C14H15N3O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Gly-Gly-MCA |
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| Synonym | More Synonyms |
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H-Gly-Gly-AMC hydrochloride salt BiologicalActivity
| Description | Gly-Gly-AMC is a fluorogenic peptide substrate. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus[1][2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| In Vitro | Gly-Gly-AMC can be hydrolyzed at very low levels by SW480 and T47D cell extracts[1]. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus[2]. |
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| References | [1]. Berger Y, et al. Determination of intracellular prolyl/glycyl proteases in intact living human cells and protoporphyrin IX production as a reporter system. Chem Biol. 2005 Aug;12(8):867-72. [2]. Wildeboer D, et al. Characterization of bacterial proteases with a panel of fluorescent peptide substrates. Anal Biochem. 2009 Jan 15;384(2):321-8. |
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Chemical & Physical Properties
| Molecular Formula | C14H15N3O4 |
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| Molecular Weight | 289.28700 |
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| Exact Mass | 289.10600 |
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| PSA | 114.43000 |
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| LogP | 1.27900 |
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| InChIKey | LPLILQIZVFKNJC-UHFFFAOYSA-N |
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| SMILES | Cc1cc(=O)oc2cc(NC(=O)CNC(=O)CN)ccc12 |
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Synonyms
| gg-mca |
| H-Gly-Gly-AMC |
| Glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)glycinamide |
