Introduction：Basic information about CAS 1553977-42-6|Btk inhibitor 1 (R enantiomer hydrochloride), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Btk inhibitor 1 (R enantiomer hydrochloride) |
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| CAS Number | 1553977-42-6 | Molecular Weight | 422.91100 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C22H23ClN6O | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Btk inhibitor 1R enantiomer Hcl is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.IC50 value:Target: BtkFrom PCT Int. Appl. (2012), WO 2012158843 A2 20121122. |
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| Related Catalog | Signaling Pathways >>Protein Tyrosine Kinase/RTK >>BtkResearch Areas >>Cancer |
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| References | [1]. PCT Int. Appl. (2012), WO 2012158843 A2 20121122. |
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Chemical & Physical Properties
| Molecular Formula | C22H23ClN6O |
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| Molecular Weight | 422.91100 |
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| Exact Mass | 422.16200 |
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| PSA | 90.88000 |
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| LogP | 5.50430 |
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| InChIKey | ATLAMSZMAHXMSQ-PKLMIRHRSA-N |
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| SMILES | Cl.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCCNC1 |
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| Storage condition | 2-8℃ |
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Synonyms
| Btk inhibitor 1 (R enantiomer hydrochloride) |
| 3-(4-Phenoxyphenyl)-1-(3R)-3-piperidinyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride (1:1) |
