CAS 1438492-26-2|ciraparantag

Introduction：Basic information about CAS 1438492-26-2|ciraparantag, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. ciraparantag BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	ciraparantag
CAS Number	1438492-26-2	Molecular Weight	512.69600
Density	/	Boiling Point	/
Molecular Formula	C₂₂H₄₈N₁₂O₂	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	di-arginine piperazine
Synonym	More Synonyms

ciraparantag BiologicalActivity

Description	Ciraparantag is a thrombin and factor Xa inhibitors as well as to heparin-based anticoagulants through non-covalent hydrogen bonding and charge interactions. It is reported to antagonize the effects of all coagulants except VKAs and agratroban. [1][2]
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Cardiovascular Disease
References	[1]. Arundhati Das et al. Novel antidotes for target specific oral anticoagulants. Exp Hematol Oncol, 2015, 4: 25. [2]. Tiffany Y Hu et al. Reversing anticoagulant effects of novel oral anticoagulants: role of ciraparantag, andexanet alfa, and idarucizumab. Vasc Health Risk Manag, 2016, 12: 35-44.

Description

Ciraparantag is a thrombin and factor Xa inhibitors as well as to heparin-based anticoagulants through non-covalent hydrogen bonding and charge interactions. It is reported to antagonize the effects of all coagulants except VKAs and agratroban. [1][2]

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Cardiovascular Disease

References

[1]. Arundhati Das et al. Novel antidotes for target specific oral anticoagulants. Exp Hematol Oncol, 2015, 4: 25.

[2]. Tiffany Y Hu et al. Reversing anticoagulant effects of novel oral anticoagulants: role of ciraparantag, andexanet alfa, and idarucizumab. Vasc Health Risk Manag, 2016, 12: 35-44.

Chemical & Physical Properties

Molecular Formula	C₂₂H₄₈N₁₂O₂
Molecular Weight	512.69600
Exact Mass	512.40200
PSA	240.52000
LogP	1.23780
InChIKey	HRDUUSCYRPOMSO-ROUUACIJSA-N
SMILES	NC(N)=NCCCC(N)C(=O)NCCCN1CCN(CCCNC(=O)C(N)CCCN=C(N)N)CC1
Storage condition	2-8℃

Synonyms

2-amino-5-guanidino-pentanoic acid (3'-{4-[3-(2-amino-5-guanidino-pentanoylamino)-propyl]-piperazin-1-yl}-propyl)-amide

ciraparantag

(2S,2'S)-N,N'-(1,4-Piperazinediyldi-3,1-propanediyl)bis[2-amino-5-[(aminoiminomethyl)amino]pentanamide]

PER977

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