CAS 1421373-62-7|Mutant EGFR inhibitor

Introduction:Basic information about CAS 1421373-62-7|Mutant EGFR inhibitor, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMutant EGFR inhibitor
CAS Number1421373-62-7Molecular Weight520.02600
Density/Boiling Point/
Molecular FormulaC27H30ClN7O2Melting Point/
MSDS/Flash Point/

Names

NameN-(5-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide
SynonymMore Synonyms

Mutant EGFR inhibitor BiologicalActivity

DescriptionMutant EGFR inhibitor is a potent and selective mutant EGFR inhibitor extracted from patent WO 2013014448 A1; inhibits EGFRL858R, EGFRExon 19 deletion and EGFRT790M.
Related CatalogResearch Areas >>Cancer
Target

EGFRL858R

EGFRExon 19 deletion

EGFRT790M

References

[1]. WO 2013014448 A1

Chemical & Physical Properties

Molecular FormulaC27H30ClN7O2
Molecular Weight520.02600
Exact Mass519.21500
PSA98.41000
LogP5.29880
Storage condition2-8℃

Synonyms

N-[5-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-2-(2-dimethylaminoethylmethylamino)-4-methoxyphenyl]prop-2-enamide
Mutant EGFR inhibitor
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