Introduction：Basic information about CAS 1453071-47-0|KDM2/7-IN-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | KDM2/7-IN-1 |
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| CAS Number | 1453071-47-0 | Molecular Weight | 285.37900 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C15H27NO4 | Melting Point | 87 °C |
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| MSDS | / | Flash Point | / |
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Names
| Name | ncdm-64 |
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| Synonym | More Synonyms |
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KDM2/7-IN-1 BiologicalActivity
| Description | KDM2/7-IN-1 (TC-E 5002) is a selective histone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.2, 1.2, 6.8, 55, 83, >100 and >120 μM for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A and KDM4A respectively). KDM2/7-IN-1 inhibits growth of HeLa and KYSE-150 cancer cells in vitro[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Epigenetics >>Histone Demethylase |
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| References | [1]. Suzuki T, et al. Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity. J Med Chem. 2013 Sep 26;56(18):7222-31. |
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Chemical & Physical Properties
| Melting Point | 87 °C |
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| Molecular Formula | C15H27NO4 |
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| Molecular Weight | 285.37900 |
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| Exact Mass | 285.19400 |
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| PSA | 77.84000 |
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| LogP | 3.20970 |
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| InChIKey | NEHSERYKENINRH-UHFFFAOYSA-N |
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| SMILES | O=C(O)CCN(O)C(=O)CCCCCCCCC1CC1 |
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Synonyms
| 3-(9-cyclopropyl-N-hydroxynonanamido)propanoic acid |
| 3-(N-hydroxy-9-cyclopropylnonanamido)propanoic acid |
