CAS 142759-74-8|Anemarsaponin BIII

Introduction:Basic information about CAS 142759-74-8|Anemarsaponin BIII, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameAnemarsaponin BIII
CAS Number142759-74-8Molecular Weight903.058
Density1.4±0.1 g/cm3Boiling Point1023.7±65.0 °C at 760 mmHg
Molecular FormulaC45H74O18Melting Point/
MSDS/Flash Point572.9±34.3 °C

Names

Namepseudoprototimosaponin AIII
SynonymMore Synonyms

Anemarsaponin BIII BiologicalActivity

DescriptionTimosaponin B III is a major bioactive steroidal saponin isolated from Anemarrhena asphodeloides Bge, and exhibits anti-inflammatory, anti-platelet aggregative and anti-depressive effects[1][2][3].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/ImmunologyResearch Areas >>Neurological Disease
References

[1]. Zhang XL, et al. Timosaponin B-III exhibits antidepressive activity in a mouse model of postpartum depression by the regulation of inflammatory cytokines, BNDF signaling and synaptic plasticity. Exp Ther Med. 2017 Oct;14(4):3856-3861.

[2]. Zhao YF, et al. New transformation pathway and cytotoxic derivatives from the acid hydrolysis of timosaponin B III. Nat Prod Res. 2018 Nov 20:1-7.

[3]. Kang LP, et al. Steroidal glycosides from the rhizomes of Anemarrhena asphodeloides and their antiplateletaggregation activity. Planta Med. 2012 Apr;78(6):611-6.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point1023.7±65.0 °C at 760 mmHg
Molecular FormulaC45H74O18
Molecular Weight903.058
Flash Point572.9±34.3 °C
Exact Mass902.487488
PSA287.14000
LogP2.01
Vapour Pressure0.0±0.6 mmHg at 25°C
Index of Refraction1.626
InChIKeyROHLIYKWVMBBFX-GFMVILKCSA-N
SMILESCC1=C(CCC(C)COC2OC(CO)C(O)C(O)C2O)OC2CC3C4CCC5CC(OC6OC(CO)C(O)C(O)C6OC6OC(CO)C(O)C(O)C6O)CCC5(C)C4CCC3(C)C12
Storage condition2-8℃

Synonyms

β-D-Galactopyranoside, (3β,5β,25S)-26-(β-D-glucopyranosyloxy)furost-20(22)-en-3-yl 2-O-β-D-glucopyranosyl-
(3β,5β,25S)-26-(β-D-Glucopyranosyloxy)furost-20(22)-en-3-yl 2-O-β-D-glucopyranosyl-β-D-galactopyranoside
anemarrhenasaponin IV
timosaponin B-III
timosaponin B
timosaponin BIII
timosaponin B III
anemarsaponin BIII
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