Introduction：Basic information about CAS 6879-05-6|Dehydroeburicoic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dehydroeburicoic acid |
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| CAS Number | 6879-05-6 | Molecular Weight | 468.71100 |
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| Density | 1.07±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C31H48O3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Dehydroeburicoic acid |
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| Synonym | More Synonyms |
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Dehydroeburicoic acid BiologicalActivity
| Description | Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Apoptosis >>CaspaseResearch Areas >>Inflammation/Immunology |
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| Target | Caspase-3 |
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| In Vivo | Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed cells with a GI50 value of 40 μM[1]. |
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| References | [1]. Kang HM, et al. Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed rat2 cells and induces apoptosis through caspase-3 pathway. Life Sci. 2006 Jan 2;78(6):607-13. |
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Chemical & Physical Properties
| Density | 1.07±0.1 g/cm3 |
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| Molecular Formula | C31H48O3 |
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| Molecular Weight | 468.71100 |
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| Exact Mass | 468.36000 |
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| PSA | 57.53000 |
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| LogP | 7.56580 |
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| InChIKey | ONFPYGOMAADWAT-OXUZYLMNSA-N |
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| SMILES | C=C(CCC(C(=O)O)C1CCC2(C)C3=CCC4C(C)(CCC(O)C4(C)C)C3=CCC12C)C(C)C |
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| Water Solubility | Insuluble (6.1E-6 g/L) (25 ºC) |
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Synonyms
| (R)-2-((3S,5R,10S,13R,14R,17R)-3-Hydroxy-4,4,10,13,14-pentamethyl-2,3,4,5,6,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methyl-5-methylene-heptanoic acid |
| 3β-Hydroxy-eburica-7,9(11),24(28)-trien-21-saeure |
| dehydroeburicoic acid |
| 3β-Hydroxy-24-methylen-lanosta-7,9(11)-dien-21-saeure |
| 3β-hydroxy-eburica-7,9(11),24(28)-trien-21-oic acid |
