CAS 120278-22-0|salvinolone

Introduction：Basic information about CAS 120278-22-0|salvinolone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. salvinolone BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	salvinolone
CAS Number	120278-22-0	Molecular Weight	314.41900
Density	1.18±0.1 g/cm3	Boiling Point	498.8±45.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₆O₃	Melting Point	253-254 °C
MSDS	/	Flash Point	/

Names

Name	salvinolone
Synonym	More Synonyms

salvinolone BiologicalActivity

Description	Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h[1][2].
Related Catalog	Research Areas >>CancerResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Bacterial
References	[1]. Mingfeng Xu, et al. Bioactive diterpenes from Clerodendrum kaichianum. Nat Prod Commun. 2011 Jan;6(1):3-5. [2]. EnriqueAlvarez-Manzaneda, et al. First synthesis of picealactone C. A new route toward taxodione-related terpenoids from abietic acid. Tetrahedron Letters, Volume 48, Issue 6, 5 February 2007, Pages 989-992.

Description

Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h[1][2].

Related Catalog

Research Areas >>CancerResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Bacterial

References

[1]. Mingfeng Xu, et al. Bioactive diterpenes from Clerodendrum kaichianum. Nat Prod Commun. 2011 Jan;6(1):3-5.

[2]. EnriqueAlvarez-Manzaneda, et al. First synthesis of picealactone C. A new route toward taxodione-related terpenoids from abietic acid. Tetrahedron Letters, Volume 48, Issue 6, 5 February 2007, Pages 989-992.

Chemical & Physical Properties

Density	1.18±0.1 g/cm3
Boiling Point	498.8±45.0 °C at 760 mmHg
Melting Point	253-254 °C
Molecular Formula	C₂₀H₂₆O₃
Molecular Weight	314.41900
Exact Mass	314.18800
PSA	57.53000
LogP	4.81170
InChIKey	NPADGWOASIJKSB-FQEVSTJZSA-N
SMILES	CC(C)c1cc2c(c(O)c1O)C1(C)CCCC(C)(C)C1=CC2=O

Synonyms

5,6-Dihydroxy-7-isopropyl-1,1,4a-trimethyl-2,3,4,4a-tetrahydro-1H-phenanthren-9-one

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