Introduction：Basic information about CAS 20958-15-0|Isotanshinone IIA, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Isotanshinone IIA |
|---|
| CAS Number | 20958-15-0 | Molecular Weight | 294.34400 |
|---|
| Density | / | Boiling Point | 471.1±45.0 °C(Predicted) |
|---|
| Molecular Formula | C19H18O3 | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | isotanshinone IIA |
|---|
| Synonym | More Synonyms |
|---|
Isotanshinone IIA BiologicalActivity
| Description | Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. |
|---|
| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>PhosphataseResearch Areas >>Metabolic DiseaseNatural Products >>Others |
|---|
| Target | IC50: 11.4 μM (PTP1B)[1]. |
|---|
| References | [1]. Han YM, et al. PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza. Biol Pharm Bull. 2005 Sep;28(9):1795-7. |
|---|
Chemical & Physical Properties
| Boiling Point | 471.1±45.0 °C(Predicted) |
|---|
| Molecular Formula | C19H18O3 |
|---|
| Molecular Weight | 294.34400 |
|---|
| Exact Mass | 294.12600 |
|---|
| PSA | 47.28000 |
|---|
| LogP | 3.97730 |
|---|
| InChIKey | QHGPIJMPUOVBOL-UHFFFAOYSA-N |
|---|
| SMILES | Cc1coc2c1C(=O)c1ccc3c(c1C2=O)CCCC3(C)C |
|---|
Safety Information
Synonyms
| 4,4,8-Trimethyl-2,3-dihydro-1H,4H-10-oxa-cyclopenta[b]phenanthrene-7,11-dione |
| Isotanshinon-II |
| isotanshinone II |
