Introduction：Basic information about CAS 80930-74-1|Zingibroside R1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Zingibroside R1 |
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| CAS Number | 80930-74-1 | Molecular Weight | 794.96500 |
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| Density | 1.37±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C42H66O14 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 28-O-deglucosyl-chikusetsusaponin V |
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| Synonym | More Synonyms |
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Zingibroside R1 BiologicalActivity
| Description | Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity[1].Zingibroside R1 possesses some anti-HIV-1 activity.Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM)[2]. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>HIVResearch Areas >>InfectionResearch Areas >>Metabolic Disease |
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| Target | IC50: 91.3 μM (2-DG uptake)[1] |
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| References | [1]. Yoshizaki K, et al. Saponins composition of rhizomes, taproots, and lateral roots of Satsuma-ninjin (Panax japonicus). Chem Pharm Bull (Tokyo). 2013;61(3):344-50. Epub 2012 Dec 28 [2]. Hasegawa H, et al. Inhibitory effect of some triterpenoid saponins on glucose transport in tumor cells and its application to in vitro cytotoxic and antiviral activities. Planta Med. 1994 Jun;60 (3):240-3. |
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Chemical & Physical Properties
| Density | 1.37±0.1 g/cm3 |
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| Molecular Formula | C42H66O14 |
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| Molecular Weight | 794.96500 |
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| Exact Mass | 794.44500 |
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| PSA | 232.90000 |
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| LogP | 2.97430 |
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| InChIKey | WJQOMUVKRDJBGZ-COUNGWPASA-N |
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| SMILES | CC1(C)CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CCC(OC6OC(C(=O)O)C(O)C(O)C6OC6OC(CO)C(O)C(O)C6O)C(C)(C)C5CCC43C)C2C1 |
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| Storage condition | 2-8℃ |
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| Water Solubility | Insuluble (1.8E-4 g/L) (25 ºC) |
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Synonyms
| 28-deglucosyl-chikusetsusaponin V |
| Zingibroside R1 |
| polysciassaponin P5 |
| 3-O-[O-β-D-glucopyranosyl-(1->2)-(β-D-glucopyranosyluronic acid)]oleanolic acid |
| polysciasaponin P5 |
