Introduction：Basic information about CAS 1271738-74-9|Febuxostat impurity 6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Febuxostat impurity 6 |
|---|
| CAS Number | 1271738-74-9 | Molecular Weight | 362.443 |
|---|
| Density | 1.2±0.1 g/cm3 | Boiling Point | 516.9±60.0 °C at 760 mmHg |
|---|
| Molecular Formula | C18H22N2O4S | Melting Point | / |
|---|
| MSDS | / | Flash Point | 266.4±32.9 °C |
|---|
Names
| Name | Ethyl 2-{3-[(E)-(hydroxyimino)methyl]-4-isobutoxyphenyl}-4-methyl-1,3-thiazole-5-carboxylate |
|---|
| Synonym | More Synonyms |
|---|
Febuxostat impurity 6 BiologicalActivity
| Description | Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1]. |
|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
|---|
| References | [1]. Leonid Metsger, et al. Processes for preparing febuxostat. WO2011031409A1. |
|---|
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|
| Boiling Point | 516.9±60.0 °C at 760 mmHg |
|---|
| Molecular Formula | C18H22N2O4S |
|---|
| Molecular Weight | 362.443 |
|---|
| Flash Point | 266.4±32.9 °C |
|---|
| Exact Mass | 362.130035 |
|---|
| LogP | 5.57 |
|---|
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
|---|
| Index of Refraction | 1.583 |
|---|
| Water Solubility | Insuluble (6.2E-3 g/L) (25 ºC) |
|---|
Synonyms
| Ethyl 2-{3-[(E)-(hydroxyimino)methyl]-4-isobutoxyphenyl}-4-methyl-1,3-thiazole-5-carboxylate |
| 5-Thiazolecarboxylic acid, 2-[3-[(E)-(hydroxyimino)methyl]-4-(2-methylpropoxy)phenyl]-4-methyl-, ethyl ester |
| 2-[3-[(Hydroxyimino)methyl]-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid ethyl ester |
| Febuxostat Impurity 10 |
