Introduction：Basic information about CAS 1415566-28-7|Rivaroxaban Impurity 3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Rivaroxaban Impurity 3 |
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| CAS Number | 1415566-28-7 | Molecular Weight | 401.44 |
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| Density | 1.400±0.06 g/cm3 (20 ºC 760 Torr) | Boiling Point | 758.0±60.0 °C(Predicted) |
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| Molecular Formula | C19H19N3O5S | Melting Point | 216-218 °C |
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| MSDS | / | Flash Point | / |
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Names
| Name | Rivaroxaban Impurity 3 |
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| Synonym | More Synonyms |
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Rivaroxaban Impurity 3 BiologicalActivity
| Description | Dechloro Rivaroxaban is a highly selective, orally active inhibitor of Factor Xa. Dechloro Rivaroxaban inhibits human free FXa with a Ki of 0.4 nM. Dechloro Rivaroxaban inhibits prothrombinase activity and fibrin-associated FXa activity with IC50s of 2.1 nM and 92 nM, respectively[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Metabolic Enzyme/Protease >>Factor Xa |
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| References | [1]. Lang D, et al. In vitro metabolism of rivaroxaban, an oral, direct factor Xa inhibitor, in liver microsomes and hepatocytes of rats, dogs, and humans. Drug Metab Dispos. 2009 May;37(5):1046-55. |
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Chemical & Physical Properties
| Density | 1.400±0.06 g/cm3 (20 ºC 760 Torr) |
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| Boiling Point | 758.0±60.0 °C(Predicted) |
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| Melting Point | 216-218 °C |
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| Molecular Formula | C19H19N3O5S |
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| Molecular Weight | 401.44 |
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| InChIKey | SJVCANNMDYDYLN-HNNXBMFYSA-N |
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| SMILES | O=C(NCC1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1)c1cccs1 |
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Synonyms
| N-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide |
