Introduction：Basic information about CAS 59092-91-0|Albaspidin AP, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Albaspidin AP |
|---|
| CAS Number | 59092-91-0 | Molecular Weight | 470.956 |
|---|
| Density | 1.8±0.1 g/cm3 | Boiling Point | 434.4±45.0 °C at 760 mmHg |
|---|
| Molecular Formula | C9H7Cl4F8NO3 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 216.5±28.7 °C |
|---|
Names
| Name | 1,7-dichloro-2,6-bis(chloro(difluoro)methyl)-1,1,7,7-tetrafluoro-2,6-dihydroxy-4-heptanone oxime |
|---|
| Synonym | More Synonyms |
|---|
Albaspidin AP BiologicalActivity
| Description | Albaspidin AP inhibits fatty acid synthase (FAS) with an IC50 value of 71.7 μM. Fatty acid synthase (FAS) is emerging as a potential therapeutic target for cancer and obesity[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>Fatty Acid Synthase (FAS)Research Areas >>Metabolic Disease |
|---|
| References | [1]. MinKyun Na, et al. Fatty acid synthase inhibitory activity of acylphloroglucinols isolated from Dryopteris crassirhizoma. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4738-42. |
|---|
Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
|---|
| Boiling Point | 434.4±45.0 °C at 760 mmHg |
|---|
| Molecular Formula | C9H7Cl4F8NO3 |
|---|
| Molecular Weight | 470.956 |
|---|
| Flash Point | 216.5±28.7 °C |
|---|
| Exact Mass | 468.905243 |
|---|
| LogP | 10.44 |
|---|
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
|---|
| Index of Refraction | 1.439 |
|---|
| InChIKey | KINDGCLGBSBXOD-UHFFFAOYSA-N |
|---|
| SMILES | CCC(=O)C1=C(O)C(CC2=C(O)C(C)(C)C(=O)C(C(C)=O)=C2O)=C(O)C(C)(C)C1=O |
|---|
Synonyms
| 1,7-dichloro-2,6-bis(chloro(difluoro)methyl)-1,1,7,7-tetrafluoro-2,6-dihydroxy-4-heptanone oxime |
| 4-Heptanone, 2,6-bis(chlorodifluoromethyl)-1,7-dichloro-2,6-dihydroxy-1,1,7,7-tetrafluoro-, oxime |
| 1,7-Dichloro-2,6-bis[chloro(difluoro)methyl]-1,1,7,7-tetrafluoro-4-(hydroxyimino)-2,6-heptanediol |
| 4-Heptanone, 1,7-dichloro-2,6-bis(chlorodifluoromethyl)-1,1,7,7-tetrafluoro-2,6-dihydroxy-, oxime |
| Albaspidin AP |
