Introduction：Basic information about CAS 756526-02-0|Fmoc-N-amido-PEG8-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fmoc-N-amido-PEG8-acid |
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| CAS Number | 756526-02-0 | Molecular Weight | 663.75200 |
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| Density | 1.190±0.06 g/cm3 | Boiling Point | / |
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| Molecular Formula | C34H49NO12 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Fmoc-NH-PEG8-CH2CH2COOH |
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| Synonym | More Synonyms |
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Fmoc-N-amido-PEG8-acid BiologicalActivity
| Description | Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Fulcher JM, et al. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Org Biomol Chem. 2019 Dec 28;17(48):10237-10244. |
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Chemical & Physical Properties
| Density | 1.190±0.06 g/cm3 |
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| Molecular Formula | C34H49NO12 |
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| Molecular Weight | 663.75200 |
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| Exact Mass | 663.32500 |
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| PSA | 149.47000 |
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| LogP | 3.52350 |
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| InChIKey | VYXGUCLTEWCVRY-UHFFFAOYSA-N |
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| SMILES | O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21 |
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| Storage condition | 2-8°C， Seal |
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| Water Solubility | Slightly soluble (2.5 g/L) (25 ºC) |
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Synonyms
| 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester |
| 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azahentriacontan-31-oic acid |
| Fmoc-N-amido-PEG8-acid |
