Introduction：Basic information about CAS 1236288-25-7|DSPE-PEG-Folate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | DSPE-PEG-Folate |
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| CAS Number | 1236288-25-7 | Molecular Weight | 6226.47 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C287H558N11O127P | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[folate(polyethylene glycol)-5000] (aMMoniuM salt) |
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DSPE-PEG-Folate BiologicalActivity
| Description | DSPE-PEG-Folate (Mw 3350) is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research[1][2][3]. |
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| Related Catalog | Research Areas >>Cancer |
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| References | [1]. Werner ME, et, al. Folate-targeted nanoparticle delivery of chemo- and radiotherapeutics for the treatment of ovarian cancer peritoneal metastasis. Biomaterials. 2011 Nov;32(33):8548-54. [2]. Li Y, et, al. Self-Assembled Nanoparticles Based on Amphiphilic Anticancer Drug-Phospholipid Complex for Targeted Drug Delivery and Intracellular Dual-Controlled Release. ACS Appl Mater Interfaces. 2015 Aug 19;7(32):17573-81. [3]. Patlolla RR, et al. Folate-targeted etoposide-encapsulated lipid nanospheres. J Drug Target. 2008 May;16(4):269-75. |
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Chemical & Physical Properties
| Molecular Formula | C287H558N11O127P |
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| Molecular Weight | 6226.47 |
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| InChIKey | WXIKCKLNMQSVPC-UHFFFAOYSA-N |
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| SMILES | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)OCCOCCNC(=O)CCC(NC(=O)c1ccc(NCC2=NC3C(=O)NC(=N)N=C3N=C2)cc1)C(=O)O)OC(=O)CCCCCCCCCCCCCCCCC.N |
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Safety Information
