CAS 152290-47-6|5',5-Difluoro BAPTA tetrapotassium

Introduction:Basic information about CAS 152290-47-6|5',5-Difluoro BAPTA tetrapotassium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name5',5-Difluoro BAPTA tetrapotassium
CAS Number152290-47-6Molecular Weight664.7757264
Density/Boiling Point/
Molecular FormulaC22H18F2N2O10.4KMelting Point/
MSDS/Flash Point/

Names

NameN,N'-[1,2-Ethanediylbis[oxy(4-fluoro-2,1-phenylene)]]bis[N-(carboxymethyl)glycine] tetrapotassium salt

5',5-Difluoro BAPTA tetrapotassium BiologicalActivity

Description5,5'-Difluoro BAPTA tetrapotassium is a difluoro-derivative of BAPTA (HY-100168). 5,5'-Difluoro BAPTA tetrapotassium shows large 19F NMR chemical shifts upon chelating divalent cations. 5,5'-Difluoro BAPTA tetrapotassium has high selectivity for Ca2+. 5,5'-Difluoro BAPTA tetrapotassium can inhibit the growth of pollen tube[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroFe2+ ion concentrations were measured following addition of 5 mM 5,5'-Difluoro BAPTA tetrapotassium to the culture medium. Fe2+ forms a complex with 5,5'-Difluoro BAPTA tetrapotassium (Kd=50 nM) that exhibits a characteristic peak down-field from biological ions such as Ca2+ and Zn2+[3].
References

[1]. Bar-Shir A, et al. Metal ion sensing using ion chemical exchange saturation transfer 19F magnetic resonance imaging. J Am Chem Soc. 2013 Aug 21;135(33):12164-7.

[2]. Pierson ES, et al. Pollen tube growth is coupled to the extracellular calcium ion flux and the intracellular calcium gradient: effect of BAPTA-type buffers and hypertonic media. Plant Cell. 1994 Dec;6(12):1815-28.

[3]. Kostellow AB, et al. Iron-catalyzed lipid peroxidation in aortic cells in vitro: protective effect of extracellular magnesium. Atherosclerosis. 2004 Jul;175(1):15-22.

Chemical & Physical Properties

Molecular FormulaC22H18F2N2O10.4K
Molecular Weight664.7757264
InChIKeyXBUXXFVULDFAOM-UHFFFAOYSA-J
SMILESO=C([O-])CN(CC(=O)[O-])c1ccc(F)cc1OCCOc1cc(F)ccc1N(CC(=O)[O-])CC(=O)[O-].[K+].[K+].[K+].[K+]
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