Introduction：Basic information about CAS 35960-33-9|Ganglioside GM2 Asialo Mixture, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ganglioside GM2 Asialo Mixture |
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| CAS Number | 35960-33-9 | Molecular Weight | 1093.4 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C56H104N2O18 | Melting Point | / |
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| MSDS | USA | Flash Point | / |
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Names
| Name | Asialoganglioside GM<sub>2</sub> |
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| Synonym | More Synonyms |
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Ganglioside GM2 Asialo Mixture BiologicalActivity
| Description | Ganglioside GM2 asialo (asialo-GM2) is a glycosphingolipid containing three monosaccharide residues and one fatty acid of variable chain length, but lacks the sialic acid residue present on ganglioside M2. Asialo-GM2 is found at low or undetectable levels in normal human brains, but it accumulates in the brains of patients with Tay-Sachs disease and Sandhoff disease, which are expressed as lysosomal β- A neurodegenerative disorder characterized by hexosaminidase A and B deficiency. It also binds to various bacteria, including Pseudomonas isolated from cystic fibrosis patients. The Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable length. |
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| Related Catalog | Research Areas >>Others |
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Chemical & Physical Properties
| Molecular Formula | C56H104N2O18 |
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| Molecular Weight | 1093.4 |
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| InChIKey | FOCMISOLVPZNSV-CYSIEEFGSA-N |
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| SMILES | CCCCCCCCCCCCCC=CC(O)C(COC1OC(CO)C(OC2OC(CO)C(OC3OC(CO)C(O)C(O)C3NC(C)=O)C(O)C2O)C(O)C1O)NC(=O)CCCCCCCCCCCCCCCCC |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Articles26
More Articles
| Asialo GM-2 developed on the fatty streak of atherosclerotic aorta detected by a novel monoclonal antibody (ASH1a/256C). Ann. N. Y. Acad. Sci. 748 , 277-81; discussion 281-2, (1995)
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| Catabolism of asialo-GM2 in man and mouse. Specificity of human/mouse chimeric GM2 activator proteins. J. Biol. Chem. 274(40) , 28612-8, (1999) Tay-Sachs disease is an inborn lysosomal disease characterized by excessive cerebral accumulation of GM2. The catabolism of GM2 to GM3 in man requires beta-hexosaminidase A (HexA) and a protein cofact... | |
| Optimal conditions to radiolabel (3H or 14C) aminosugar-containing glycosphingolipids by de-N-acetylation and re-N-acetylation. Biochim. Biophys. Acta 1244(2-3) , 418-22, (1995) The optimal conditions were examined for selective re-N-acetylation with 14C or 3H.acetic anhydride of de-N-acetylated aminosugar-containing glycosphingolipids. Re-N-acetylation, which is nearly quant... | |
Synonyms
