CAS 54576-84-0|Nuclease P1

Introduction:Basic information about CAS 54576-84-0|Nuclease P1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameNuclease P1
CAS Number54576-84-0Molecular Weight/
Density/Boiling Point/
Molecular Formula/Melting Point/
MSDSUSAFlash Point/

Names

NameNuclease P1 from Penicillium citrinum
SynonymMore Synonyms

Nuclease P1 BiologicalActivity

DescriptionNuclease P1 is a single-stranded specific endonuclease, it hydrolyzes nucleic acids into 5'-mononucleotides and cleaves the single-stranded region of a double-stranded nucleic acid. Nuclease P1 is one of the most well-known single stranded specific nucleases in the field of molecular biology, it is widely used in the pharmaceutical and food industries[1].
Related CatalogResearch Areas >>Others
References

[1]. Mitiushkina NV, et al. Preparation of Duplex Sequencing Libraries for Archival Paraffin-Embedded Tissue Samples Using Single-Strand-Specific Nuclease P1. Int J Mol Sci. 2022 Apr 21;23(9):4586.  

Chemical & Physical Properties

Storage condition2-8°C

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport

Articles48

More Articles
Hydroxyl-radical-induced oxidation of 5-methylcytosine in isolated and cellular DNA.

Nucleic Acids Res. 42(11) , 7450-60, (2014)

The methylation and oxidative demethylation of cytosine in CpG dinucleotides plays a critical role in the regulation of genes during cell differentiation, embryogenesis and carcinogenesis. Despite its...

Effect of 8-oxoguanine glycosylase deficiency on aflatoxin B1 tumourigenicity in mice.

Mutagenesis 30 , 401-9, (2015)

The mycotoxin aflatoxin B1 (AFB1) may initiate cancer by causing oxidatively damaged DNA, specifically by causing 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) lesions. Base excision repair removes th...

SAW1 is required for SDSA double-strand break repair in S. cerevisiae.

Biochem. Biophys. Res. Commun. 445(3) , 602-7, (2014)

SAW1, coding for Saw1, is required for single-strand annealing (SSA) DNA double-strand break (DSB) repair in Saccharomycescerevisiae. Saw1 physically associates with Rad1 and Rad52 and recruits the Ra...

Synonyms

EINECS 253-443-9
MFCD00131010
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