CAS 9002-61-3|APL (hormone)
| Common Name | APL (hormone) | ||
|---|---|---|---|
| CAS Number | 9002-61-3 | Molecular Weight | 232.40422 |
| Density | / | Boiling Point | / |
| Molecular Formula | C17H28 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS08 | Signal Word | Warning |
Names
| Name | Chorionic gonadotropin |
|---|---|
| Synonym | More Synonyms |
APL (hormone) BiologicalActivity
| Description | APL (hormone) (Ambinon) is a gonadotropin that can be isolated from the anterior pituitary gland. APL (hormone) has potential applications in ovarian and follicular development[1]. |
|---|---|
| Related Catalog | Research Areas >>Endocrinology |
| In Vivo | APL (hormone) (0.5 mL/d；肌肉注射；6 d) 导致母鸡卵泡发生退化，卵巢受损[1]。 APL (hormone) (0.25 mL/d；肌肉注射；9 d) 在小雏鸡中显著促进了卵巢的增重[1]。 APL (hormone) (0.5 mL/d；肌肉注射；9 d) 导致小雏鸡的卵泡出现退化的迹象[1]。 APL (hormone) (0.2 mL/d；1、2、3、4、5、6 和 7 weeks) 对接受垂体切除术的大鼠的体重、尾部长度和眼睛屈光度无显著影响[2]。 Animal Model: White Leghorn, Barred Plymouth Rock, and Barred Plymouth Rock X New Hampshire crossbred hens and pullets[1]. Dosage: 0.25 mL/d and 0.5 mL/d. Administration: Intramuscular injection; 6 d and 9 d. Result: Hindered the normal development of the ovaries and follicles. |
| References | [1]. Phillips R E. Ovarian response of hens and pullets to injections of Ambinon[J]. Poultry Science, 1943, 22(5): 368-373. [2]. Alphen CC, et al. Endocrine influences on the refraction of the eyes of young rats. Ophthalmologica. 1976;173(3-4):328-32. |
Chemical & Physical Properties
| Molecular Formula | C17H28 |
|---|---|
| Molecular Weight | 232.40422 |
| Appearance of Characters | lyophilized powder |
| InChIKey | XFOOPZIJVVDYHI-BQBZGAKWSA-N |
| SMILES | NC(CCCC(=O)NC(CS)C(=O)NCC(=O)O)C(=O)O |
| Storage condition | 2-8°C |
| Water Solubility | H2O: soluble1ML/vial |
Safety Information
| Symbol | GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H361 |
| Precautionary Statements | P280 |
| Hazard Codes | B,Xn |
| Risk Phrases | 63-62 |
| Safety Phrases | 22-36-36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | MD6953000 |
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| [Comparison of the amounts of hCG and PMSG to induce ovulation in 50% of the animals, mice, Syrian hamsters and rats]. Jikken Dobutsu. 41(2) , 153-9, (1992) On the day of diestrus, female mice, syrian hamsters and rats, showing regular 4-day estrous cycles, were injected with hCG or PMSG and were inspected for the presence of ovulation the following day. ... |
Synonyms
| EINECS 232-660-2 |
| MFCD00130797 |
| HCG |
