Introduction：Basic information about CAS 80506-64-5|Methoxypolyethylene glycol amine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methoxypolyethylene glycol amine |
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| CAS Number | 80506-64-5 | Molecular Weight | 3400(Average) |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 583.6±45.0 °C at 760 mmHg |
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| Molecular Formula | (C2H4O)nC3H9NO | Melting Point | 58-61 °C(lit.) |
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| MSDS | USA | Flash Point | 291.3±22.4 °C |
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Names
| Name | Methoxypolyethylene glycol amine |
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| Synonym | More Synonyms |
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Methoxypolyethylene glycol amine BiologicalActivity
| Description | mPEG-amine (MW 3400) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR). |
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| Related Catalog | Research Areas >>Cancer |
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| References | [1]. Han X, et al. 9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: preparation and evaluation in vitro. Int J Pharm. 2009 May 8;372(1-2):125-31. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 583.6±45.0 °C at 760 mmHg |
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| Melting Point | 58-61 °C(lit.) |
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| Molecular Formula | (C2H4O)nC3H9NO |
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| Molecular Weight | 3400(Average) |
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| Flash Point | 291.3±22.4 °C |
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| Exact Mass | 559.357 |
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| LogP | -4.59 |
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| Appearance of Characters | Granular Solid |
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| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
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| Index of Refraction | 1.458 |
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| InChIKey | MSKSQCLPULZWNO-UHFFFAOYSA-N |
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| SMILES | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN |
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| Storage condition | −20°C |
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| Water Solubility | Soluble in water |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | C |
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| Safety Phrases | S22;S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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Articles1
More Articles
| Preparation of micelle-forming polymer-drug conjugates. Bioconjug. Chem. 3 , 295, (1992) Adriamycin, a hydrophobic anticancer drug, was conjugated with poly(ethylene oxide)-poly(aspartic acid) block copolymers composed of various lengths of each block copolymer segment ranging from 1000 t... | |
Synonyms
| MFCD00131599 |
| Methoxypoly(ethylene glycol) aMine |
| mPEG-NH2 |
| MPEG12-amine |
| MPEG12-NH2 |
| 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-amine |
| m-PEG12-amine |
| α-methoxy-ω-amino poly (ethylene glycol) |
