CAS 9002-71-5|tsh
| Common Name | tsh | ||
|---|---|---|---|
| CAS Number | 9002-71-5 | Molecular Weight | 422.436 |
| Density | / | Boiling Point | / |
| Molecular Formula | C18H26N6O6 | Melting Point | / |
| MSDS | USA | Flash Point | / |
Names
| Name | Thyrotropic hormone from bovine pituitary |
|---|---|
| Synonym | More Synonyms |
tsh BiologicalActivity
| Description | Thyrotropin (TSH) is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid[1][2]. |
|---|---|
| Related Catalog | Research Areas >>EndocrinologySignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
| References | [1]. Wolf G. The regulation of the thyroid-stimulating hormone of the anterior pituitary gland by thyroid hormone and by 9-cis-retinoic acid. Nutr Rev. 2002 Nov;60(11):374-7. [2]. Vassart G, et al. The thyrotropin receptor and the regulation of thyrocyte function and growth. Endocr Rev. 1992 Aug;13(3):596-611. |
Chemical & Physical Properties
| Molecular Formula | C18H26N6O6 |
|---|---|
| Molecular Weight | 422.436 |
| Exact Mass | 422.191376 |
| Appearance of Characters | lyophilized powder |
| Storage condition | 2-8°C |
Safety Information
| Hazard Codes | B |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | XP3581600 |
Articles108
More Articles| Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species. Endocrinology 156(4) , 1540-51, (2015) Na+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the first and rate-limiting step in the biosynthesis of the thyroid hormones. The expression and function of NIS in thyroid cel... | |
| Effects of magnesium on cytomorphology and enzyme activities in thyroid of rats. Indian J. Exp. Biol. 52(8) , 787-92, (2014) Till date knowledge regarding the effects of high dietary magnesium on thyroid gland is incomprehensive though certain epidemiological studies reported development of thyroid gland dysfunctions in peo... | |
| Extreme phenotypic variability of thyroid dysgenesis in six new cases of congenital hypothyroidism due to PAX8 gene loss-of-function mutations. Eur. J. Endocrinol. 171(4) , 499-507, (2014) Within the last two decades, heterozygous loss-of-function PAX8 mutations have been reported in patients with a wide degree of thyroid gland dysfunction and growth despite the presence of identical mu... |
Synonyms
| L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-, acetate (1:1) |
| MFCD00166060 |
| 5-Oxo-L-prolyl-L-histidyl-L-prolinamide acetate (1:1) |
| EINECS 232-664-4 |
