Introduction：Basic information about CAS 9008-97-3|PHA (Phytohemagglutinins), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | PHA (Phytohemagglutinins) |
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| CAS Number | 9008-97-3 | Molecular Weight | / |
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| Density | / | Boiling Point | / |
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| Molecular Formula | / | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
PHA (Phytohemagglutinins) BiologicalActivity
| Description | Phytohemagglutinin (PHA) is a lectin, obtained from the red kidney bean that binds to the membranes of T-cells, stimulates metabolic activity, cell division, and involves inflammatory pathways. Phytohemagglutinin (PHA) induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3[1][2][3]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerResearch Areas >>Inflammation/Immunology |
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| References | [1]. Movafagh A, et al. The Significance Application of Indigenous Phytohemagglutinin (PHA) Mitogen on Metaphase and Cell Culture Procedure. Iran J Pharm Res. 2011 Fall;10(4):895-903. [2]. Merlo JL, et al. Food Restriction Affects Inflammatory Response and Nutritional State in Tuco-tucos (Ctenomys talarum). J Exp Zool A Ecol Genet Physiol. 2016 Dec;325(10):675-687. [3]. Kochubei TO, et al. Isolectins of phytohemagglutinin are able to induce apoptosis in HEp-2 carcinoma cells in vitro. Exp Oncol. 2015 Jun;37(2):116-9. |
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Chemical & Physical Properties
| Appearance of Characters | salt-free, lyophilized powder |
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| Storage condition | 2-8°C |
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| Water Solubility | PBS: 2 mg/mL |
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Safety Information
| Hazard Codes | Xi |
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| Safety Phrases | 22-24/25 |
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| RTECS | TJ3470000 |
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