Introduction：Basic information about CAS 853220-52-7|BML 284, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | BML 284 |
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| CAS Number | 853220-52-7 | Molecular Weight | 350.371 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 623.4±65.0 °C at 760 mmHg |
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| Molecular Formula | C19H18N4O3 | Melting Point | / |
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| MSDS | / | Flash Point | 330.8±34.3 °C |
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Names
| Name | N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine |
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| Synonym | More Synonyms |
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BML 284 BiologicalActivity
| Description | BML-284 is selective and cell-permeable Wnt signaling activator. |
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| Related Catalog | Signaling Pathways >>Stem Cell/Wnt >>WntResearch Areas >>Cancer |
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| References | [1]. Liu J, et al. A small-molecule agonist of the Wnt signaling pathway. Angew Chem Int Ed Engl. 2005 Mar 18;44(13):1987-90. [2]. Wang H, et al. 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine is an anti-inflammatory TLR-2, -4 and -5 response mediator in human monocytes. Inflamm Res. 2016 Jan;65(1):61-9. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 623.4±65.0 °C at 760 mmHg |
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| Molecular Formula | C19H18N4O3 |
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| Molecular Weight | 350.371 |
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| Flash Point | 330.8±34.3 °C |
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| Exact Mass | 350.137878 |
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| LogP | 3.72 |
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| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
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| Index of Refraction | 1.684 |
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| InChIKey | FABQUVYDAXWUQP-UHFFFAOYSA-N |
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| SMILES | COc1cccc(-c2cc(NCc3ccc4c(c3)OCO4)nc(N)n2)c1 |
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| Storage condition | -20℃ |
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Synonyms
| N-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine |
| MFCD09908087 |
| 2,4-Pyrimidinediamine, N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)- |
| BML-284 |
| Wnt agonist 1 |
| CID 11210285 hydrochloride |
