Introduction：Basic information about CAS 918407-35-9|Avoralstat, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Avoralstat |
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| CAS Number | 918407-35-9 | Molecular Weight | 513.544 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C28H27N5O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | AVORALSTAT |
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| Synonym | More Synonyms |
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Avoralstat BiologicalActivity
| Description | Avoralstat is an oral plasma kallikrein (PKK) inhibitor, used for the treatment of hereditary angioedema. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Others |
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| References | [1]. Aygoren-Pursun E, et al. Prophylaxis of hereditary angioedema attacks: A randomized trial of oral plasma kallikrein inhibition with avoralstat. J Allergy Clin Immunol. 2016 Sep;138(3):934-936.e5. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Molecular Formula | C28H27N5O5 |
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| Molecular Weight | 513.544 |
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| Exact Mass | 513.201233 |
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| LogP | 0.80 |
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| Index of Refraction | 1.673 |
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Synonyms
| 3-{2-[(4-Carbamimidoylphenyl)carbamoyl]-5-methoxy-4-vinylphenyl}-6-[(cyclopropylmethyl)carbamoyl]-2-pyridinecarboxylic acid |
| UNII-UX17773O15 |
| AVORALSTAT |
| 2-Pyridinecarboxylic acid, 3-[2-[[[4-[(Z)-aminoiminomethyl]phenyl]amino]carbonyl]-4-ethenyl-5-methoxyphenyl]-6-[[(cyclopropylmethyl)amino]carbonyl]- |
