CAS 9050-76-4|Ribonuclease H, from Escherichia coli
| Common Name | Ribonuclease H, from Escherichia coli | ||
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| CAS Number | 9050-76-4 | Molecular Weight | / |
| Density | / | Boiling Point | / |
| Molecular Formula | / | Melting Point | / |
| MSDS | USA | Flash Point | / |
Names
| Name | RIBONUCLEASE H |
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| Synonym | More Synonyms |
Ribonuclease H, from Escherichia coli BiologicalActivity
| Description | Ribonuclease H is an enzyme degrading the RNA moiety of DNA-RNA hybrids[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisResearch Areas >>Others |
| References | [1]. Hausen P, et al. Ribonuclease H. An enzyme degrading the RNA moiety of DNA-RNA hybrids. Eur J Biochem. 1970 Jun;14(2):278-83. |
Chemical & Physical Properties
| Storage condition | −20°C |
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Safety Information
| RIDADR | NONH for all modes of transport |
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| WGK Germany | 1 |
Articles3
More Articles| Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors. Clin. Infect. Dis. 55(5) , 737-45, (2012) It is not known how often mutations in the connection and ribonuclease H domains of reverse transcriptase (RT) emerge with failure of first-line antiretroviral therapy (ART) in subtype C human immunod... | |
| Metallobiochemistry of the magnesium ion. Characterization of the essential metal-binding site in Escherichia coli ribonuclease H. Eur. J. Biochem. 219 , 253-60, (1994) Ribonuclease H (Escherichia coli) contains one strong magnesium-binding site, as determined by metal-titration experiments monitored by high field 1H-NMR and also by direct titration calorimetry. Kine... | |
| Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity Bioorg. Med. Chem. Lett. 22(12) , 3988-92, (2012) We report herein the synthesis of a series of 3-hydroxyquinolin-2(1H)-one derivatives. Esters and amide groups were introduced at position 4 of the basis scaffold and some modulations of the benzenic ... |
Synonyms
| MFCD00132186 |
