CAS 261521-21-5|PAR-3 (1-6) amide (mouse) trifluoroacetate salt

Introduction：Basic information about CAS 261521-21-5|PAR-3 (1-6) amide (mouse) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	PAR-3 (1-6) amide (mouse) trifluoroacetate salt
CAS Number	261521-21-5	Molecular Weight	576.60
Density	1.4±0.1 g/cm3	Boiling Point	1229.5±65.0 °C at 760 mmHg
Molecular Formula	C₂₅H₃₆N₈O₈	Melting Point	/
MSDS	/	Flash Point	697.4±34.3 °C

Names

Name	L-Seryl-L-phenylalanyl-L-asparaginylglycylglycyl-L-prolinamide
Synonym	More Synonyms

BiologicalActivity

Description	SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.)
Related Catalog	Research Areas >>OthersSignaling Pathways >>GPCR/G Protein >>Protease-Activated Receptor (PAR)

Description

SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.)

Related Catalog

Research Areas >>OthersSignaling Pathways >>GPCR/G Protein >>Protease-Activated Receptor (PAR)

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	1229.5±65.0 °C at 760 mmHg
Molecular Formula	C₂₅H₃₆N₈O₈
Molecular Weight	576.60
Flash Point	697.4±34.3 °C
Exact Mass	576.265625
LogP	-2.38
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.602

Synonyms

L-Seryl-L-phenylalanyl-L-asparaginylglycylglycyl-L-prolinamide

L-Prolinamide, L-seryl-L-phenylalanyl-L-asparaginylglycylglycyl-

SFNGGP-NH2 PAR3 Tethered Ligand (Murine) / Activates PAR1 and PAR2

PAR-3 (1-6) amide (mouse)

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