Introduction：Basic information about CAS 19536-25-5|2-O-Acetyl-20-hydroxyecdysone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-O-Acetyl-20-hydroxyecdysone |
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| CAS Number | 19536-25-5 | Molecular Weight | 522.67 |
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| Density | 1.26±0.1 g/cm3 | Boiling Point | 707.3±60.0 °C |
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| Molecular Formula | C29H46O8 | Melting Point | 218-220 ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | 20-hydroxyecdysone, 2-acetate |
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| Synonym | More Synonyms |
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2-O-Acetyl-20-hydroxyecdysone BiologicalActivity
| Description | 2-O-Acetyl-20-hydroxyecdysone, an ecdysterones in insects and terrestrial plants, inhibits amyloid-β42 (Aβ42)-induced cytotoxicity. 2-O-Acetyl-20-hydroxyecdysone could decrease Aβ oligomer formation through promotion of fibrogenesis, transforming Aβ oligomers to the low-toxicity fibrils[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| References | [1]. Yang SG, et al. Diverse ecdysterones show different effects on amyloid-β42 aggregation but all uniformly inhibit amyloid-β42-induced cytotoxicity. J Alzheimers Dis. 2010;22(1):107-17. |
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Chemical & Physical Properties
| Density | 1.26±0.1 g/cm3 |
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| Boiling Point | 707.3±60.0 °C |
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| Melting Point | 218-220 ºC |
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| Molecular Formula | C29H46O8 |
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| Molecular Weight | 522.67 |
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| Exact Mass | 522.319 |
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| PSA | 144.52 |
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| LogP | 2.4248 |
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| InChIKey | TXLUXHSVMYTTCI-FORVDKSSSA-N |
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| SMILES | CC(=O)OC1CC2(C)C(CC1O)C(=O)C=C1C2CCC2(C)C(C(C)(O)C(O)CCC(C)(C)O)CCC12O |
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| Water Solubility | Very slightly soluble (0.24 g/L) (25 ºC) |
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Safety Information
Synonyms
| β-Ecdysone 2-acetate |
| 2-O-Acetyl-20-hydroxyecdysone |
