CAS 400604-12-8|20-Hydroxyganoderic acid G

Introduction:Basic information about CAS 400604-12-8|20-Hydroxyganoderic acid G, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name20-Hydroxyganoderic acid G
CAS Number400604-12-8Molecular Weight548.67
Density1.31±0.1 g/cm3(Predicted)Boiling Point760.1±60.0 °C(Predicted)
Molecular FormulaC30H44O9Melting Point/
MSDS/Flash Point/

Names

Name20-Hydroxyganoderic acid G

20-Hydroxyganoderic acid G BiologicalActivity

Description20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC50 of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the drug discovery of nerve inflammation diseases associated with microglia activated by LPS[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References

[1]. Jiao Y, et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3556-61.

Chemical & Physical Properties

Density1.31±0.1 g/cm3(Predicted)
Boiling Point760.1±60.0 °C(Predicted)
Molecular FormulaC30H44O9
Molecular Weight548.67
InChIKeyHHCQRNABFNZPFW-PVWQPZRVSA-N
SMILESCC(CC(=O)CC(C)(O)C1CC(=O)C2(C)C3=C(C(=O)C(O)C12C)C1(C)CCC(O)C(C)(C)C1CC3O)C(=O)O
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