Introduction：Basic information about CAS 1159588-21-2|(Z)-Pitavastatin calcium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (Z)-Pitavastatin calcium |
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| CAS Number | 1159588-21-2 | Molecular Weight | 420.4528232 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C25H24FNO4.1/2Ca | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (Z)-Pitavastatin Calcium Salt |
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| Synonym | More Synonyms |
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(Z)-Pitavastatin calcium BiologicalActivity
| Description | (Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor.Cardiovasc Drug Rev. 2003 Fall;21(3):199-215. |
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Chemical & Physical Properties
| Molecular Formula | C25H24FNO4.1/2Ca |
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| Molecular Weight | 420.4528232 |
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| InChIKey | RHGYHLPFVJEAOC-HDCUBKASSA-L |
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| SMILES | O=C([O-])CC(O)CC(O)C=Cc1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1.O=C([O-])CC(O)CC(O)C=Cc1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1.[Ca+2] |
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Synonyms
