Introduction：Basic information about CAS 1562338-42-4|LMI070, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | LMI070 |
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| CAS Number | 1562338-42-4 | Molecular Weight | 393.482 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 660.0±55.0 °C at 760 mmHg |
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| Molecular Formula | C22H27N5O2 | Melting Point | / |
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| MSDS | / | Flash Point | 353.0±31.5 °C |
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Names
| Name | LMI070 |
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| Synonym | More Synonyms |
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LMI070 BiologicalActivity
| Description | LMI070 (Branaplam) is a highly potent, selective and orally active small molecule SMN2 splicing modulator. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisResearch Areas >>Cancer |
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| References | [1]. Palacino J, et al. SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice. Nat Chem Biol. 2015 Jul;11(7):511-517. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 660.0±55.0 °C at 760 mmHg |
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| Molecular Formula | C22H27N5O2 |
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| Molecular Weight | 393.482 |
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| Flash Point | 353.0±31.5 °C |
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| Exact Mass | 393.216461 |
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| LogP | 2.86 |
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| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
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| Index of Refraction | 1.576 |
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| Storage condition | -20℃ |
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Synonyms
| branaplam |
| P12R69543A |
| Phenol, 5-(1H-pyrazol-4-yl)-2-[6-[(2,2,6,6-tetramethyl-4-piperidinyl)oxy]-3-pyridazinyl]- |
| 5-(1H-Pyrazol-4-yl)-2-{6-[(2,2,6,6-tetramethyl-4-piperidinyl)oxy]-3-pyridazinyl}phenol |
| LMI070 |
