CAS 1187451-41-7|Omidenepag

Introduction：Basic information about CAS 1187451-41-7|Omidenepag, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Omidenepag BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Omidenepag
CAS Number	1187451-41-7	Molecular Weight	478.524
Density	1.4±0.1 g/cm3	Boiling Point	769.4±70.0 °C at 760 mmHg
Molecular Formula	C₂₃H₂₂N₆O₄S	Melting Point	/
MSDS	/	Flash Point	419.1±35.7 °C

Names

Name	omidenepag
Synonym	More Synonyms

Omidenepag BiologicalActivity

Description	Omidenepag,a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. Omidenepag shows binding affinities (IC50) 10 nM for h-EP2[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>GPCR/G Protein >>Prostaglandin Receptor
Target	EP2:1.1 nM (EC50) h-EP1:10 nM (IC50) h-EP4:5480 nM (IC50)
References	[1]. Iwamura R, et al. Identification of a Selective, Non-Prostanoid EP2 Receptor Agonist for the Treatment of Glaucoma: Omidenepag and its Prodrug Omidenepag Isopropyl. J Med Chem. 2018 Aug 9;61(15):6869-6891.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	769.4±70.0 °C at 760 mmHg
Molecular Formula	C₂₃H₂₂N₆O₄S
Molecular Weight	478.524
Flash Point	419.1±35.7 °C
Exact Mass	478.142334
LogP	1.75
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.680
InChIKey	YHGSTSNEOJUIRN-UHFFFAOYSA-N
SMILES	O=C(O)CNc1cccc(CN(Cc2ccc(-n3cccn3)cc2)S(=O)(=O)c2cccnc2)n1

Synonyms

UNII-Z95F9F9LU4

Z95F9F9LU4

UR-7276

Glycine, N-[6-[[[[4-(1H-pyrazol-1-yl)phenyl]methyl](3-pyridinylsulfonyl)amino]methyl]-2-pyridinyl]-

N-[6-({[4-(1H-Pyrazol-1-yl)benzyl](3-pyridinylsulfonyl)amino}methyl)-2-pyridinyl]glycine

N-{6-[(N-{[4-(1H-pyrazol-1-yl)phenyl]methyl}pyridine-3-sulfonamido)methyl]pyridin-2-yl}glycine

omidenepag

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