CAS 19716-61-1|8-Oxycoptisine

Introduction：Basic information about CAS 19716-61-1|8-Oxycoptisine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 8-Oxycoptisine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	8-Oxycoptisine
CAS Number	19716-61-1	Molecular Weight	335.310
Density	1.6±0.0 g/cm3	Boiling Point	617.5±0.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₃NO₅	Melting Point	/
MSDS	/	Flash Point	327.3±0.0 °C

Names

Name	6,7-Dihydro-4H-[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquinolino[3,2-a]isoquinolin-4-one
Synonym	More Synonyms

8-Oxycoptisine BiologicalActivity

Description	8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Others
In Vitro	8-Oxocoptisine has cytotoxicity against NCI-N87 (IC50=20.31 μM) and has no cytotoxicity against Caco-2 (IC50>100 μM)[1].
References	[1]. Ping Qian, et al. Five new alkaloids from Coptidis Rhizoma-Euodiae Fructus couple and their cytotoxic activities against gastrointestinal cancer cells. Fitoterapia. 2014 Mar;93:74-80.

Chemical & Physical Properties

Density	1.6±0.0 g/cm3
Boiling Point	617.5±0.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₃NO₅
Molecular Weight	335.310
Flash Point	327.3±0.0 °C
Exact Mass	335.079010
LogP	4.65
Vapour Pressure	0.0±0.0 mmHg at 25°C
Index of Refraction	1.768
InChIKey	UCAFJBSQKXVPDX-UHFFFAOYSA-N
SMILES	O=c1c2c3c(ccc2cc2n1CCc1cc4c(cc1-2)OCO4)OCO3
Storage condition	2-8℃

Synonyms

6,7-Dihydro-4H-[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquinolino[3,2-a]isoquinolin-4-one

4H-[1,3]Benzodioxolo[5,6-a]-1,3-benzodioxolo[4,5-g]quinolizin-4-one, 6,7-dihydro-

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