Introduction：Basic information about CAS 219846-31-8|Radequinil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Radequinil |
|---|
| CAS Number | 219846-31-8 | Molecular Weight | 334.33 |
|---|
| Density | 1.3±0.1 g/cm3 | Boiling Point | / |
|---|
| Molecular Formula | C18H14N4O3 | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | Radequinil |
|---|
| Synonym | More Synonyms |
|---|
Radequinil BiologicalActivity
| Description | Radequinil (AC-3933) is a benzodiazepine receptor (BzR) partial inverse agonist. AC-3933 binds to GABA(-) and GABA(+) ligand with Kis of 5.15 and 6.11 nM, respectively[1]. |
|---|
| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>GABA ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>GABA Receptor |
|---|
| Target | Ki: 5.15±0.39 nM (GABA(-) ligand), 6.11±0.26 nM (GABA(+) ligand)[1] |
|---|
| References | [1]. Hashimoto T, et al. Pharmacological properties of AC-3933, a novel benzodiazepine receptor partial inverse agonist. Neuroscience. 2014 Jan 3;256:352-9. |
|---|
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|
| Molecular Formula | C18H14N4O3 |
|---|
| Molecular Weight | 334.33 |
|---|
| Exact Mass | 334.106598 |
|---|
| LogP | 2.54 |
|---|
| Index of Refraction | 1.620 |
|---|
| InChIKey | JQOFKKWHXGQABB-UHFFFAOYSA-N |
|---|
| SMILES | COc1cccc(-c2nccc3[nH]c(=O)c(-c4noc(C)n4)cc23)c1 |
|---|
Synonyms
| UNII-2G222T03EY |
| 2G222T03EY |
| Radequinil |
| 1,6-Naphthyridin-2(1H)-one, 5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)- |
| 5-(3-Methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin-2(1H)-one |
| 5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-1,2-dihydro-1,6-naphthyridine |
