CAS 193807-58-8|gelatinase a

Introduction：Basic information about CAS 193807-58-8|gelatinase a, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. gelatinase a BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	gelatinase a
CAS Number	193807-58-8	Molecular Weight	381.445
Density	1.3±0.1 g/cm3	Boiling Point	595.9±60.0 °C at 760 mmHg
Molecular Formula	C₂₁H₁₉NO₄S	Melting Point	/
MSDS	/	Flash Point	314.2±32.9 °C

Names

Name	N-(4-Biphenylylsulfonyl)-D-phenylalanine
Synonym	More Synonyms

gelatinase a BiologicalActivity

Description	MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase (MMP-9 and MMP-2) inhibitor with IC50s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>MMP
References	[1]. Y Tamura, et al. Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives. J Med Chem. 1998 Feb 12;41(4):640-9.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	595.9±60.0 °C at 760 mmHg
Molecular Formula	C₂₁H₁₉NO₄S
Molecular Weight	381.445
Flash Point	314.2±32.9 °C
Exact Mass	381.103485
LogP	4.47
Appearance of Characters	powder \| light brown
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.627
InChIKey	JBYHBQIDTNHWJF-HXUWFJFHSA-N
SMILES	O=C(O)C(Cc1ccccc1)NS(=O)(=O)c1ccc(-c2ccccc2)cc1
Storage condition	2-8°C

Safety Information

Hazard Codes	B,Xi
Risk Phrases	36/37/38-42
Safety Phrases	23-26-36-24/25
WGK Germany	2

Synonyms

D-Phenylalanine, N-([1,1'-biphenyl]-4-ylsulfonyl)-

N-(Biphenyl-4-ylsulfonyl)-D-phenylalanine

N-(4-Biphenylylsulfonyl)-D-phenylalanine

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