CAS 1216539-56-8|Venlafaxine-d10 hydrochloride
Introduction：Basic information about CAS 1216539-56-8|Venlafaxine-d10 hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Venlafaxine-d10 hydrochloride | ||
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| CAS Number | 1216539-56-8 | Molecular Weight | 323.92433778 |
| Density | / | Boiling Point | / |
| Molecular Formula | C17H18ClD10NO2 | Melting Point | / |
| MSDS | / | Flash Point | / |
Names
| Name | D,L-Venlafaxine-d10 Hydrochloride |
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Venlafaxine-d10 hydrochloride BiologicalActivity
| Description | Venlafaxine-d10 (Wy 45030-d10) is the deuterium labeled Venlafaxine hydrochloride. Venlafaxine (Wy 45030) hydrochloride is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1][2]. |
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| Related Catalog | Research Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>Serotonin Transporter |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80. [3]. Goeringer KE, et al. Postmortem tissue concentrations of venlafaxine. Forensic Sci Int. 2001 Sep 15;121(1-2):70-5. |
Chemical & Physical Properties
| Molecular Formula | C17H18ClD10NO2 |
|---|---|
| Molecular Weight | 323.92433778 |
