Introduction：Basic information about CAS 122654-30-2|2-Chloro-3’-deoxy-3’-fluoroadenosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Chloro-3’-deoxy-3’-fluoroadenosine |
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| CAS Number | 122654-30-2 | Molecular Weight | 303.68 |
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| Density | 2.1±0.1 g/cm3 | Boiling Point | 550.0±60.0 °C at 760 mmHg |
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| Molecular Formula | C10H11ClFN5O3 | Melting Point | / |
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| MSDS | / | Flash Point | 286.4±32.9 °C |
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Names
| Name | 3'-Deoxy-3'-fluoro-2-chloroadenosine |
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| Synonym | More Synonyms |
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2-Chloro-3’-deoxy-3’-fluoroadenosine BiologicalActivity
| Description | 2-Chloro-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 2.1±0.1 g/cm3 |
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| Boiling Point | 550.0±60.0 °C at 760 mmHg |
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| Molecular Formula | C10H11ClFN5O3 |
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| Molecular Weight | 303.68 |
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| Flash Point | 286.4±32.9 °C |
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| Exact Mass | 303.053436 |
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| LogP | 0.71 |
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| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
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| Index of Refraction | 1.844 |
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| InChIKey | IRHXEJNSFOBHLE-DXTOWSMRSA-N |
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| SMILES | Nc1nc(Cl)nc2c1ncn2C1OC(CO)C(F)C1O |
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Synonyms
| 2-Chloro-3'-deoxy-3'-fluoroadenosine |
| Adenosine, 2-chloro-3'-deoxy-3'-fluoro- |
