Introduction：Basic information about CAS 1233234-77-9|Boc-NH-PEG11-NH2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Boc-NH-PEG11-NH2 |
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| CAS Number | 1233234-77-9 | Molecular Weight | 644.792 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 667.6±55.0 °C at 760 mmHg |
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| Molecular Formula | C29H60N2O13 | Melting Point | / |
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| MSDS | / | Flash Point | 357.5±31.5 °C |
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Names
| Name | Boc-NH-PEG11-CH2CH2NH2 |
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| Synonym | More Synonyms |
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Boc-NH-PEG11-NH2 BiologicalActivity
| Description | Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 667.6±55.0 °C at 760 mmHg |
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| Molecular Formula | C29H60N2O13 |
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| Molecular Weight | 644.792 |
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| Flash Point | 357.5±31.5 °C |
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| Exact Mass | 644.409546 |
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| LogP | -3.03 |
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| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
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| Index of Refraction | 1.467 |
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Synonyms
| Boc-PEG-amine (n=11) |
| 2-Methyl-2-propanyl (35-amino-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacont-1-yl)carbamate |
| MFCD03453245 |
| Carbamic acid, N-(35-amino-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacont-1-yl)-, 1,1-dimethylethyl ester |
