Introduction：Basic information about CAS 1239588-11-4|Methyl propionate-PEG12, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methyl propionate-PEG12 |
|---|
| CAS Number | 1239588-11-4 | Molecular Weight | 632.735 |
|---|
| Density | 1.1±0.1 g/cm3 | Boiling Point | 646.1±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C28H56O15 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 190.2±23.6 °C |
|---|
Names
| Name | m-PEG13-acid |
|---|
| Synonym | More Synonyms |
|---|
Methyl propionate-PEG12 BiologicalActivity
| Description | Methyl propionate-PEG12 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | PEGs Alkyl/ether |
|---|
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
|---|
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|
| Boiling Point | 646.1±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C28H56O15 |
|---|
| Molecular Weight | 632.735 |
|---|
| Flash Point | 190.2±23.6 °C |
|---|
| Exact Mass | 632.361938 |
|---|
| LogP | -4.47 |
|---|
| Vapour Pressure | 0.0±4.4 mmHg at 25°C |
|---|
| Index of Refraction | 1.461 |
|---|
Synonyms
| Methyl 1-hydroxy-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxanonatriacontan-39-oate |
| 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxanonatriacontan-39-oic acid, 1-hydroxy-, methyl ester |
